GC-MS Analysis of Five Commonly Used Herbal Formulations Sold in Anambra State, Southeast, Nigeria


  • Chinedu J. Ikem Department of Pharmaceutical Microbiology & Biotechnology, Faculty of Pharmaceutical Sciences, David Umahi Federal University of Health Sciences, Uburu, Ebonyi State, Nigeria.
  • Angus N. Oli Department of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Nigeria
  • Ifunanya Nwaigwe Department of Pharmaceutical Microbiology & Biotechnology, Faculty of Pharmacy, Madonna University, Elele, River State, Nigeria
  • Cyril Ogbiko Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, David Umahi Federal University of Health Sciences, Uburu, Ebonyi State, Nigeria
  • Charles O. Esimone epartment of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Nigeria




Anticancer, Antimicrobial, Antiplasmodial, Antioxidant, Bioactive constituents, Herbal formulations


Plant extracts have been known to possess multiple bioactive compounds with therapeutic uses. Gas chromatography-mass spectrometry (GC-MS) was used in the current study to characterize the bioactive constituents of five (5) commercially available herbal formulations. The National Institute of Standard Technology Database was used to analyze the mass spectrum of the five commonly available herbal formulations sold in Anambra State, Southeast, Nigeria. The GC-MS analysis showed the presence of thirty-five (35) bioactive compounds. The identified compounds were listed in the following order; Compound name, peak area (%), molecular weight, molecular formula, and biological activities. The bioactive compounds present include; Quinolone, Oleic acid, Hexadecanoic acid, Phenolic, Dodecanoic acid, and, phthalic acid which are believed to possess antiplasmodial, antimicrobial, antiviral, anticancer, antioxidant, and antifungal activities. This study confirmed that the five herbal formulations have rich bioactive compounds that could benefit mankind, although some of the synthetic compounds isolated are of major health concern.


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How to Cite

Ikem, C. J., Oli, A. N., Nwaigwe, I., Ogbiko, C., & Esimone, C. O. (2024). GC-MS Analysis of Five Commonly Used Herbal Formulations Sold in Anambra State, Southeast, Nigeria. Tropical Journal of Phytochemistry and Pharmaceutical Sciences, 3(2), 201–207. https://doi.org/10.26538/tjpps/v3i2.7